PACSIN1 Antikörper (AA 240-390)

Produktnummer ABIN7269626

Produktdetails anti-PACSIN1 Antikörper

Target: PACSIN1 (Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1))

Bindungsspezifität: AA 240-390

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACSIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PACSIN1 Rabbit pAb

Sequenz: KRLVFLKEVL LDIKRHLNLA ENSSYIHVYR ELEQAIRGAD AQEDLRWFRS TSGPGMPMNW PQFEEWNPDL PHTTTKKEKQ PKKAEGVALT NATGAVESTS QAGDRGSVSS YDRGQPYATE WSDDESGNPF GGSETNGGAN PFEDDSKGVR V

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human PACSIN1 (NP_065855.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PACSIN1

Target: PACSIN1 (Protein Kinase C and Casein Kinase Substrate in Neurons 1 (PACSIN1))

Andere Bezeichnung: PACSIN1 (PACSIN1 Produkte)

Synonyme: MGC84055 antikoerper, sdpii antikoerper, pacsin1 antikoerper, x-PACSIN2 antikoerper, fe25d06 antikoerper, wu:fe25d06 antikoerper, zgc:114042 antikoerper, PACSIN1 antikoerper, SDPI antikoerper, A830061D09Rik antikoerper, H74 antikoerper, mKIAA1379 antikoerper, syndapin antikoerper, protein kinase C and casein kinase substrate in neurons 1 antikoerper, protein kinase C and casein kinase substrate in neurons 1 S homeolog antikoerper, protein kinase C and casein kinase substrate in neurons 2 antikoerper, protein kinase C and casein kinase substrate in neurons 1b antikoerper, PACSIN1 antikoerper, pacsin1.S antikoerper, pacsin2 antikoerper, pacsin1b antikoerper, Pacsin1 antikoerper

Hintergrund: Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT, this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis, this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity. Binds to membranes via its F-BAR domain and mediates membrane tubulation.,PACSIN1,SDPI,Signal Transduction,PACSIN1

Molekulargewicht: 50kDa

Gen-ID: 29993

UniProt: Q9BY11