PDE3A Antikörper (AA 380-660)

Produktnummer ABIN7269301

Produktdetails anti-PDE3A Antikörper

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Bindungsspezifität: AA 380-660

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: PDE3A Rabbit pAb

Sequenz: LLSTQLTFQA IHKPRVNPVT SLSENYTCSD SEESSEKDKL AIPKRLRRSL PPGLLRRVSS TWTTTTSATG LPTLEPAPVR RDRSTSIKLQ EAPSSSPDSW NNPVMMTLTK SRSFTSSYAI SAANHVKAKK QSRPGALAKI SPLSSPCSSP LQGTPASSLV SKISAVQFPE SADTTAKQSL GSHRALTYTQ SAPDLSPQIL TPPVICSSCG RPYSQGNPAD EPLERSGVAT RTPSRTDDTA QVTSDYETNN NSDSSDIVQN EDETECLREP LRKASACSTY A

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDE3A

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Andere Bezeichnung: PDE3A (PDE3A Produkte)

Synonyme: PDE3A antikoerper, Pde3a antikoerper, si:dkey-48h7.2 antikoerper, A930022O17Rik antikoerper, C87899 antikoerper, RNPDE3A antikoerper, CGI-PDE antikoerper, CGI-PDE A antikoerper, CGI-PDE-A antikoerper, phosphodiesterase 3A antikoerper, phosphodiesterase 3A, cGMP-inhibited antikoerper, cGMP-inhibited 3',5'-cyclic phosphodiesterase A antikoerper, phosphodiesterase 3A, cGMP inhibited antikoerper, PDE3A antikoerper, Pde3a antikoerper, LOC100540515 antikoerper, pde3a antikoerper

Hintergrund: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,HTNB,CGI-PDE,CGI-PDE A,CGI-PDE-A,PDE3A,Signal Transduction,PDE3A

Molekulargewicht: 125kDa

Gen-ID: 5139

UniProt: Q14432

Pathways: cAMP Metabolic Process