PPARGC1A Antikörper (C-Term)

Produktnummer ABIN7529539

Produktdetails anti-PPARGC1A Antikörper

Target: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARGC1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: PGC1α Rabbit pAb

Sequenz: FGEIEECTVN LRDDGDSYGF ITYRYTCDAF AALENGYTLR RSNETDFELY FCGRKQFFKS NYADLDSNSD DFDPASTKSK YDSLDFDSLL KEAQRSLRR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human PGC1alpha (NP_037393.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPARGC1A

Target: PPARGC1A (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))

Andere Bezeichnung: PPARGC1A (PPARGC1A Produkte)

Synonyme: PPARGC1A antikoerper, PPARGC1 antikoerper, A830037N07Rik antikoerper, ENSMUSG00000079510 antikoerper, Gm11133 antikoerper, PGC-1 antikoerper, PGC-1v antikoerper, Pgc-1alpha antikoerper, Pgc1 antikoerper, Pgco1 antikoerper, Ppargc1 antikoerper, PGC1 antikoerper, PGC1A antikoerper, LEM6 antikoerper, PGC-1(alpha) antikoerper, AVPGC-1ALPHA antikoerper, PPARG coactivator 1 alpha antikoerper, peroxisome proliferative activated receptor, gamma, coactivator 1 alpha antikoerper, PPARG coactivator 1 alpha S homeolog antikoerper, PPARGC1A antikoerper, Ppargc1a antikoerper, ppargc1a.S antikoerper

Hintergrund: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.,PPARGC1A,LEM6,PGC-1(alpha),PGC-1alpha,PGC-1v,PGC1,PGC1A,PPARGC1,PPARG coactivator 1 alpha,PGC1 alpha,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Nucleotide metabolism,Molecular processes,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,Fatty Acids,PPARGC1A

Molekulargewicht: 14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa

Gen-ID: 10891

UniProt: Q9UBK2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Brown Fat Cell Differentiation