PILRA Antikörper

Produktnummer ABIN7269157

Produktdetails anti-PILRA Antikörper

Target: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PILRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: PILRA Rabbit pAb

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PILRA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PILRA

Target: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Andere Bezeichnung: PILRA (PILRA Produkte)

Synonyme: PILRA antikoerper, FDF03 antikoerper, AV021745 antikoerper, RGD1562847 antikoerper, paired immunoglobin like type 2 receptor alpha antikoerper, paired immunoglobulin-like type 2 receptor alpha antikoerper, paired immunoglobin-like type 2 receptor alpha antikoerper, PILRA antikoerper, LOC489841 antikoerper, Pilra antikoerper

Hintergrund: Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described.,PILRA,FDF03,PILRA

Molekulargewicht: 34kDa

Gen-ID: 29992

UniProt: Q9UKJ1