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FGL1 Antikörper

FGL1 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7267179
  • Target Alle FGL1 Antikörper anzeigen
    FGL1 (Fibrinogen-Like 1 (FGL1))
    Reaktivität
    • 48
    • 25
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 64
    • 7
    • 1
    Kaninchen
    Klonalität
    • 65
    • 7
    Monoklonal
    Konjugat
    • 27
    • 13
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FGL1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 31
    • 27
    • 13
    • 13
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    FGL1 Rabbit mAb
    Kreuzreaktivität
    Human
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human FGL-1 Full length.
    Isotyp
    IgG
    Top Product
    Discover our top product FGL1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.09 % sodium azide,50 % glycerol, pH 7.4.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FGL1 (Fibrinogen-Like 1 (FGL1))
    Andere Bezeichnung
    FGL1 (FGL1 Produkte)
    Synonyme
    MGC84748 antikoerper, FGL1 antikoerper, DKFZp470A2333 antikoerper, Frep1 antikoerper, Lfire1 antikoerper, HFREP1 antikoerper, HP-041 antikoerper, LFIRE-1 antikoerper, LFIRE1 antikoerper, Mfire1 antikoerper, fibrinogen like 1 L homeolog antikoerper, fibrinogen like 1 antikoerper, fibrinogen-like 1 antikoerper, fibrinogen-like protein 1 antikoerper, fgl1.L antikoerper, FGL1 antikoerper, Fgl1 antikoerper
    Hintergrund
    Fibrinogen-like protein 1 (FGL1), a liver-secreted protein, is a major LAG-3 functional ligand independent from MHC-II. The FGL1-LAG-3 pathway maybe an important immune evasion mechanism and could contribute to current cancer immunotherapy efforts for several reasons. FGL1 inhibits antigen-specific T cell activation, and ablation of FGL1 in mice promotes T cell immunity. Blockade of the FGL1-LAG-3 interaction by monoclonal antibodies stimulates tumor immunity and is therapeutic against established mouse tumors in a receptor-ligand inter-dependent manner. FGL1 is highly produced by human cancer cells, and elevated FGL1 in the plasma of cancer patients is associated with a poor prognosis and resistance to anti-PD-1/B7-H1 therapy,FGL1,HFREP1,HP-041,LFIRE-1,LFIRE1,Cardiovascular,Blood,Coagulation,Serum Proteins,FGL1
    Molekulargewicht
    36kDa
    Gen-ID
    2267
    UniProt
    Q08830
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