DCUN1D1 Antikörper (AA 15-70)

Produktnummer ABIN7266719

Produktdetails anti-DCUN1D1 Antikörper

Target: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Bindungsspezifität: AA 15-70

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCUN1D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: DCUN1D1 Rabbit pAb

Sequenz: FMIFTQSSEK TAVSCLSQND WKLDVATDNF FQNPELYIRE SVKGSLDRKK LEQLYN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 15-70 of human DCUN1D1 (NP_065691.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DCUN1D1

Target: DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))

Andere Bezeichnung: DCUN1D1 (DCUN1D1 Produkte)

Synonyme: fd19a01 antikoerper, zgc:66414 antikoerper, wu:fd19a01 antikoerper, dcun1l1 antikoerper, rp42 antikoerper, sccro antikoerper, scro antikoerper, tes3 antikoerper, DCNL1 antikoerper, DCUN1L1 antikoerper, RP42 antikoerper, SCCRO antikoerper, SCRO antikoerper, Tes3 antikoerper, Rp42 antikoerper, pTes3 antikoerper, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) antikoerper, DCN1-like protein 1 antikoerper, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog antikoerper, defective in cullin neddylation 1 domain containing 1 antikoerper, dcun1d1 antikoerper, dcnl1 antikoerper, dcun1d1.L antikoerper, DCUN1D1 antikoerper, Dcun1d1 antikoerper

Hintergrund: Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8 thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity.,DCUN1D1,DCNL1,DCUN1L1,RP42,SCCRO,SCRO,Tes3,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Ubiquitin,DCUN1D1

Molekulargewicht: 30kDa

Gen-ID: 54165

UniProt: Q96GG9