ADMA Antikörper

Produktnummer ABIN7233188

Produktdetails anti-ADMA Antikörper

Target: ADMA (Asymmetrical Dimethylarginine (ADMA))

Reaktivität: Bitte anfragen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADMA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Verwendungszweck: Anti-Asymmetric Dimethyl Arginine Mouse Monoclonal Antibody

Spezifität: This antibody reacts with free and bound ADMA. It does not cross-react with free or bound arginine or NG- monomethyl arginine.

Immunogen: Dimethyl-L-arginine

Klon: 21C7

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1-2 μg/mL
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations.
End user should determine optimal concentrations for their applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute lyophilized antibody using ultrapure to a final concentration no less than 100 μg/mL. Reconstitution with PBS or Tris buffer is acceptable if required. Protein carrier, biocide or cryopreservative can be added as needed. Aliquot and store at -20C for longterm storage. Dilute immediately prior to use.

Buffer: 0.1M Tris, 0.1M glycine, 2 % sucrose

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.

Details zu ADMA

Target: ADMA (Asymmetrical Dimethylarginine (ADMA))

Andere Bezeichnung: Asymmetric Dimethyl Arginine (ADMA Produkte)

Substanzklasse: Amino Acid

Hintergrund: Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by- product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardio- vascular health. Since raised levels of ADMA appear to be associated with adverse human health consequences for cardiovascular disease, metabolic diseases, and also a wide range of diseases of the elderly, the possible lowering of ADMA levels may have important therapeutic effects.