Aggrecan Antikörper (Cleaved-Asp369)
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- Target Alle Aggrecan (ACAN) Antikörper anzeigen
- Aggrecan (ACAN)
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Bindungsspezifität
- AA 290-370, Cleaved-Asp369
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Aggrecan Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Cleaved-Aggrecan (D369) Polyclonal Antibody
- Spezifität
- Cleaved-Aggrecan (D369) Polyclonal Antibody detects endogenous levels of fragment of activated Aggrecan protein resulting from cleavage adjacent to D369.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Immunogen
- Synthesized peptide derived from the N-terminal region of human Aggrecan at AA range: 290-370
- Isotyp
- IgG
- Top Product
- Discover our top product ACAN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
- Kommentare
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Primary Antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Target
- Aggrecan (ACAN)
- Andere Bezeichnung
- Aggrecan (ACAN Produkte)
- Synonyme
- AGC1 antikoerper, AGCAN antikoerper, CSPG1 antikoerper, CSPGCP antikoerper, MSK16 antikoerper, SEDK antikoerper, Agc antikoerper, Agc1 antikoerper, Cspg1 antikoerper, b2b183Clo antikoerper, cmd antikoerper, aggrecan antikoerper, aggrecan core protein antikoerper, ACAN antikoerper, Acan antikoerper, LOC100380783 antikoerper, AGC antikoerper
- Hintergrund
- Rabbit Anti-Cleaved-Aggrecan (D369) Polyclonal Antibody,ACAN, AGC1, CSPG1, MSK16, Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1,ACAN is a member of the aggrecan/versican proteoglycan family. Aggrecan core protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.,Aggrecan core protein
- Molekulargewicht
- observerd band 44kDa
- Gen-ID
- 176
- UniProt
- P16112
- Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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