Podocin Antikörper

Produktnummer ABIN7342489

Produktdetails anti-Podocin Antikörper

Target: Podocin (NPHS2) (Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Podocin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human NPHS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Podocin

Target: Podocin (NPHS2) (Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))

Andere Bezeichnung: NPHS2 (NPHS2 Produkte)

Synonyme: PDCN antikoerper, SRN1 antikoerper, AI790225 antikoerper, podocin antikoerper, nephrosis 2, podocin antikoerper, NPHS2, podocin antikoerper, Nphs2 antikoerper, NPHS2 antikoerper

Hintergrund:

Background: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

Aliases: nephrosis 2 antibody, Nephrosis 2, idiopathic, steroid resistant (podocin) antibody, nephrosis 2, idiopathic, steroid resistant antibody, NPHS2 antibody, NPHS2 gene antibody, PDCN antibody, PODO_HUMAN antibody, Podocin antibody, SRN1 antibody

UniProt: Q9NP85