NKp44/NCR2 Antikörper

Produktnummer ABIN7191592

Produktdetails anti-NKp44/NCR2 Antikörper

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKp44/NCR2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human NCR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:5000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NKp44/NCR2

Target: NKp44/NCR2 (NCR2) (Natural Cytotoxicity Triggering Receptor 2 (NCR2))

Andere Bezeichnung: NCR2 (NCR2 Produkte)

Synonyme: CD336 antikoerper, LY95 antikoerper, NK-p44 antikoerper, NKP44 antikoerper, dJ149M18.1 antikoerper, uncharacterized LOC609023 antikoerper, natural cytotoxicity triggering receptor 2 antikoerper, LOC609023 antikoerper, NCR2 antikoerper

Hintergrund:

Background: Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Aliases: Activating NK receptor NKp44 antibody, CD336 antibody, CD336 antigen antibody, dJ149M18.1 antibody, LY95 antibody, Lymphocyte antigen 95 (activating NK receptor, NK p44) antibody, Lymphocyte antigen 95 homolog (activating NK receptor, NK p44) antibody, Lymphocyte antigen 95 homolog antibody, Lymphocyte antigen 95, mouse, homolog of antibody, Natural cytotoxicity triggering receptor 2 antibody, Natural killer cell p44 related protein antibody, Natural killer cell p44-related protein antibody, NCR2 antibody, NCTR2_HUMAN antibody, NK cell activating receptor (NKp44) antibody, NK cell activating receptor antibody, NK cell-activating receptor antibody, NK p44 antibody, NK-p44 antibody, NKp44 antibody

UniProt: O95944