ITPR2 Antikörper
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- Target Alle ITPR2 Antikörper anzeigen
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ITPR2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of Human ITPR2
- Isotyp
- IgG
- Top Product
- Discover our top product ITPR2 Primärantikörper
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- Applikationshinweise
- ELISA:1:2000-1:10000, IHC:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ITPR2 (Inositol 1,4,5-Trisphosphate Receptor, Type 2 (ITPR2))
- Andere Bezeichnung
- ITPR2 (ITPR2 Produkte)
- Synonyme
- AI649341 antikoerper, InsP3R-2 antikoerper, InsP3R-5 antikoerper, Ip3r2 antikoerper, Itpr5 antikoerper, insP3R2 antikoerper, IP3R2 antikoerper, inositol 1,4,5-trisphosphate receptor type 2 antikoerper, inositol 1,4,5-triphosphate receptor 2 antikoerper, inositol 1,4,5-trisphosphate receptor, type 2 antikoerper, ITPR2 antikoerper, Itpr2 antikoerper
- Hintergrund
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Background: Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
Aliases: 4 antibody, 5-trisphosphate receptor antibody, Inositol 1 4 5 trisphosphate receptor type 2 antibody, Inositol 1,4,5-trisphosphate receptor type 2 antibody, Inositol 145 trisphosphate receptor type 2 antibody, InsP3 R2 antibody, InsP3R2 antibody, IP3 R2 antibody, IP3 receptor antibody, IP3 receptor isoform 2 antibody, IP3R 2 antibody, IP3R2 antibody, ITPR 2 antibody, Itpr2 antibody, ITPR2_HUMAN antibody, Type 2 inositol 1 4 5 trisphosphate receptor antibody, Type 2 inositol 1 antibody, Type 2 inositol 145 trisphosphate receptor antibody, Type 2 InsP3 receptor antibody
- UniProt
- Q14571
- Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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