SERPINA5 Antikörper (AA 251-350)

Produktnummer ABIN714836

Produktdetails anti-SERPINA5 Antikörper

Target: SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Protein C inhibitor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SERPINA5

Target: SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))

Andere Bezeichnung: Protein C inhibitor (SERPINA5 Produkte)

Synonyme: 4933415L04 antikoerper, PAI-3 antikoerper, Pci antikoerper, PAI3 antikoerper, PCI antikoerper, PCI-B antikoerper, PLANH3 antikoerper, PROCI antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antikoerper, serpin family A member 5 antikoerper, serine (or cysteine) peptidase inhibitor, clade A, member 5 antikoerper, plasma serine protease inhibitor antikoerper, SPIA5 antikoerper, SERPINA5 antikoerper, Serpina5 antikoerper, LOC480424 antikoerper

Hintergrund:

Synonyms: Acrosomal serine protease inhibitor, IPSP, PAI 3, PAI3, PCI, PLANH 3, PLANH3, Plasma serine protease inhibitor, Plasminogen activator inhibitor 3, Plasminogen activator inhibitor III, PROCI, Serpin A5, Serpin peptidase inhibitor clade A alpha 1 antiproteinase antitrypsin member 5, Serpin peptidase inhibitor clade A member 5, SerpinA5, IPSP_HUMAN.

Background: Protein C Inhibitor (PCI), a member of the serine protease inhibitor (serpin) superfamily, is abundant in plasma and other body fluids. Protein C Inhibitor inhibits a number of "arginine specific" serine proteases of the coagulation and fibrinolytic systems (including thrombin, trypsin, and activated Protein C), as well as plasma and tissue kallikreins and the sperm protease acrosin. This inhibition is regulated by glycosaminoglycans, such as heparin and heparan sulphate, and several polyanions. As well as its roles in the regulation of hemostasis and fertilisation, Protein C Inhibitor is involved in cell inflammation, proliferation, apoptosis, tumour cell migration, invasion, and metastasis. Recent studies have demonstrated an association between Protein C Inhibitor and multiple sclerosis lesions.

Gen-ID: 5104