SCN11A Antikörper (Internal Region)

Produktnummer ABIN7189376

Produktdetails anti-SCN11A Antikörper

Target: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN11A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen Affinity Purified

Immunogen: Synthetic peptide corresponding to a region derived from internal residues of Human sodium channel, voltage-gated, type XI, alpha subunit

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in pH 7.3 PBS, 0.05 % Sodium azide, 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SCN11A

Target: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Andere Bezeichnung: SCN11A (SCN11A Produkte)

Synonyme: SCN11A antikoerper, NSS2 antikoerper, NaN antikoerper, NaT antikoerper, SNS2 antikoerper, NAV1.9 antikoerper, SCN12A antikoerper, SNS-2 antikoerper, sodium voltage-gated channel alpha subunit 11 antikoerper, sodium channel protein type 11 subunit alpha antikoerper, sodium channel, voltage-gated, type XI, alpha antikoerper, SCN11A antikoerper, LOC100349709 antikoerper, Scn11a antikoerper

Hintergrund:

Background: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops, each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Aliases: hNaN antibody, NaN antibody, NAV1.9 antibody, Peripheral nerve sodium channel 5 antibody, PN 5 antibody, PN5 antibody, SCN 11A antibody, SCN 12A antibody, Scn11a antibody, SCN12A antibody, SCNBA_HUMAN antibody, Sensory neuron sodium channel 2 antibody, SNS 2 antibody, SNS2 antibody, Sodium channel protein type 11 subunit alpha antibody, Sodium channel protein type XI subunit alpha antibody, Sodium channel voltage gated type XI alpha antibody, Sodium channel voltage gated type XI alpha polypeptide antibody, Sodium channel voltage gated type XI alpha subunit antibody, Sodium channel voltage gated type XII alpha polypeptide antibody, Voltage gated sodium channel Nav1.9 antibody, Voltage gated sodium channel subunit alpha Nav1.9 antibody, Voltage-gated sodium channel subunit alpha Nav1.9 antibody

UniProt: Q9UI33