NBPF12/NBPF1/NBPF1/NBPF9 Antikörper
-
- Target
- NBPF12/NBPF1/NBPF1/NBPF9
- Reaktivität
- Human
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Applikation
- ELISA, Western Blotting (WB)
- Kreuzreaktivität
- Human
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from internal of Human NBPF1/9/10/12/14/15/16/20.
- Isotyp
- IgG
-
- Applikationshinweise
- WB:1:500-1:3000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- NBPF12/NBPF1/NBPF1/NBPF9
- Hintergrund
-
Background:
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.
Gregory S.G., Nature 441:315-321(2006).
Mei G., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.Aliases: NBPF12 antibody, COAS1 antibody, KIAA1245 antibody, Neuroblastoma breakpoint family member 12 antibody, Chromosome 1 amplified sequence 1 antibody
- UniProt
- Q5TAG4
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