BCL2L12 Antikörper

Produktnummer ABIN7183190

Produktdetails anti-BCL2L12 Antikörper

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human BCL2L12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BCL2L12

Target: BCL2L12 (BCL2-Like 12 (Proline Rich) (BCL2L12))

Andere Bezeichnung: BCL2L12 (BCL2L12 Produkte)

Synonyme: 2810475P17Rik antikoerper, 5430429M05Rik antikoerper, Bcl-L12 antikoerper, Bcl2-L12 antikoerper, BCL2 like 12 antikoerper, BCL2-like 12 (proline rich) antikoerper, BCL2L12 antikoerper, Bcl2l12 antikoerper

Hintergrund:

Background: This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.

Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].

Aliases: B2L12_HUMAN antibody, BCL 2 like 12 (proline rich) antibody, BCL 2 like 12 antibody, BCL 2 like 12 isoform 1 antibody, Bcl 2 like 12 protein antibody, Bcl 2 related proline rich protein antibody, Bcl-2-like protein 12 antibody, Bcl-2-related proline-rich protein antibody, BCL2 like 12 (proline rich) antibody, BCL2 like 12 antibody, BCL2 like 12 isoform 1 antibody, Bcl2 like 12 protein antibody, Bcl2 related proline rich protein antibody, Bcl2-L-12 antibody, BCL2L12 antibody, BPR antibody, MGC120313 antibody, MGC120314 antibody, MGC120315 antibody

UniProt: Q9HB09