S1A1 Antikörper

Produktnummer ABIN7182653

Produktdetails

Target: S1A1

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Human S100 A1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: S1A1

Hintergrund:

Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Patrick Most, J. Biol. Chem., Nov 2003, 278: 48404 - 48412.
Miki Okada, J. Biol. Chem., Feb 2004, 279: 4221 - 4233.
Melanie Boerries, Mol. Cell. Biol., Jun 2007, 27: 4365 - 4373.
Patrick Most, J. Clin. Invest., Dec 2004, 114: 1550 - 1563.

Aliases: Bpb antibody, NEF antibody, Protein S100-A1 antibody, S-100 protein alpha chain antibody, S-100 protein subunit alpha antibody, S100 alpha antibody, S100 beta antibody, S100 calcium binding protein A1 antibody, S100 calcium binding protein B antibody, S100 calcium-binding protein A1 antibody, S100 protein alpha polypeptide antibody, S100A antibody, s100a1 antibody, S100B antibody, S100beta antibody, S10A1_HUMAN antibody

UniProt: P23297