SNAIL Antikörper (AA 1-264) (Biotin)

Produktnummer ABIN7348752

Produktdetails anti-SNAIL Antikörper (Biotin)

Target: SNAIL (SNAI1)

Bindungsspezifität: AA 1-264

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Zinc finger protein SNAI1 protein (1-264AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1 (SNAI1 Produkte)

Synonyme: SLUGH2 antikoerper, SNA antikoerper, SNAH antikoerper, SNAIL antikoerper, SNAIL1 antikoerper, dJ710H13.1 antikoerper, AI194338 antikoerper, Sna antikoerper, Sna1 antikoerper, Snail antikoerper, Snail1 antikoerper, SNAI1 antikoerper, BG:DS01845.1 antikoerper, CG3956 antikoerper, Dmel\\CG3956 antikoerper, Sco antikoerper, br28 antikoerper, br29 antikoerper, l(2)35Db antikoerper, l(2)br28 antikoerper, l(2)br29 antikoerper, l(3)br28 antikoerper, l35Db antikoerper, sn antikoerper, Xsnail antikoerper, sna antikoerper, snail1 antikoerper, xSna antikoerper, Snai antikoerper, sna2 antikoerper, snail2 antikoerper, cb643 antikoerper, sna-1 antikoerper, sna1 antikoerper, snai1 antikoerper, snail1a antikoerper, zgc:109820 antikoerper, snail family transcriptional repressor 1 antikoerper, snail family zinc finger 1 antikoerper, snail homolog 1 (Drosophila) antikoerper, snail antikoerper, zinc-finger transcription factor Snail antikoerper, snail family zinc finger 1 S homeolog antikoerper, protein escargot antikoerper, transcription factor protein antikoerper, snail zinc finger protein antikoerper, snail family zinc finger 1b antikoerper, snail family zinc finger 1a antikoerper, SNAI1 antikoerper, Snai1 antikoerper, sna antikoerper, snail antikoerper, snai1.S antikoerper, LOC410464 antikoerper, snai1b antikoerper, snai1a antikoerper

Hintergrund:

Background: Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5\'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.

Aliases: dJ710H13.1 antibody, Protein sna antibody, Protein snail homolog 1 antibody, Protein snail homolog antibody, SLUGH2 antibody, SNA antibody, Sna protein antibody, SNAH antibody, SNAI antibody, snai1 antibody, SNAI1_HUMAN antibody, Snail 1 homolog antibody, Snail 1 zinc finger protein antibody, SNAIL antibody, Snail family transcriptional repressor 1 antibody, Snail homolog 1 (Drosophila) antibody, SNAIL, Drosophila, homolog of, 1 antibody, SNAIL1 antibody, Zinc finger protein SNAI1 antibody

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling