DPF1 Antikörper (AA 261-380)

Produktnummer ABIN7176590

Produktdetails anti-DPF1 Antikörper

Target: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Bindungsspezifität: AA 261-380

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Zinc finger protein neuro-d4 protein (261-380AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DPF1

Target: DPF1 (D4, Zinc and Double PHD Fingers Family 1 (DPF1))

Andere Bezeichnung: DPF1 (DPF1 Produkte)

Synonyme: zgc:110104 antikoerper, DPF1 antikoerper, req antikoerper, xReq antikoerper, neud4 antikoerper, requiem antikoerper, neuro-d4 antikoerper, BAF45b antikoerper, NEUD4 antikoerper, Neud4 antikoerper, D4, zinc and double PHD fingers family 1 antikoerper, double PHD fingers 1 antikoerper, dpf1 antikoerper, DPF1 antikoerper, Dpf1 antikoerper

Hintergrund:

Background: May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Aliases: BAF45B antibody, BRG1-associated factor 45B antibody, D4 antibody, D4 zinc and double PHD fingers family 1 antibody, DPF1 antibody, DPF1_HUMAN antibody, NEUD4 antibody, Neuro d4 homolog antibody, Zinc and double PHD fingers family 1 antibody, Zinc finger protein neuro-d4 antibody

UniProt: Q92782