LSM6 Antikörper (AA 1-80) (Biotin)

Produktnummer ABIN7174197

Produktdetails anti-LSM6 Antikörper (Biotin)

Target: LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))

Bindungsspezifität: AA 1-80

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LSM6 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human U6 snRNA-associated Sm-like protein LSm6 protein (1-80AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LSM6

Target: LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))

Andere Bezeichnung: LSM6 (LSM6 Produkte)

Synonyme: zgc:92379 antikoerper, YDR378C antikoerper, 1500031N17Rik antikoerper, 2410088K19Rik antikoerper, AI747288 antikoerper, RGD1561937 antikoerper, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog antikoerper, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated antikoerper, lsm6.S antikoerper, lsm6 antikoerper, LSM6 antikoerper, Lsm6 antikoerper

Hintergrund:

Background: Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5\'-to-3\' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3\'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).

Aliases: LSM6U6 snRNA-associated Sm-like protein LSm6 antibody

UniProt: P62312