TRPV4 Antikörper (AA 1-230)
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- Target Alle TRPV4 Antikörper anzeigen
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
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Bindungsspezifität
- AA 1-230
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRPV4 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Transient receptor potential cation channel subfamily V member 4 protein (1-230AA)
- Isotyp
- IgG
- Top Product
- Discover our top product TRPV4 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
- Andere Bezeichnung
- TRPV4 (TRPV4 Produkte)
- Synonyme
- wu:fp52e02 antikoerper, CMT2C antikoerper, HMSN2C antikoerper, OTRPC4 antikoerper, SMAL antikoerper, SPSMA antikoerper, SSQTL1 antikoerper, TRP12 antikoerper, VRL2 antikoerper, VROAC antikoerper, 0610033B08Rik antikoerper, Trp12 antikoerper, VR-OAC antikoerper, VRL-2 antikoerper, Otrpc4 antikoerper, Vroac antikoerper, transient receptor potential cation channel, subfamily V, member 4 antikoerper, transient receptor potential cation channel subfamily V member 4 antikoerper, trpv4 antikoerper, TRPV4 antikoerper, Trpv4 antikoerper
- Hintergrund
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Background: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH , citrate and phorbol esters. Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca2+ in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
Aliases: BCYM3 antibody, CMT2C antibody, HMSN2C antibody, osm 9 like TRP channel 4 antibody, Osm-9-like TRP channel 4 antibody, OSM9 like transient receptor potential channel 4 antibody, Osmosensitive transient receptor potential channel 4 antibody, OTRPC 4 antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, Transient receptor potential cation channel subfamily V member 4 antibody, Transient receptor potential protein 12 antibody, TRP 12 antibody, TRP12 antibody, TRPV 4 antibody, TrpV4 antibody, TRPV4_HUMAN antibody, Vanilloid receptor like channel 2 antibody, Vanilloid receptor like protein 2 antibody, Vanilloid receptor related osmotically activated channel antibody, Vanilloid receptor-like channel 2 antibody, Vanilloid receptor-like protein 2 antibody, Vanilloid receptor-related osmotically-activated channel antibody, VR 4 antibody, VR OAC antibody, VR-OAC antibody, VR4 antibody, VRL 2 antibody, VRL-2 antibody, VRL2 antibody, VROAC antibody
- UniProt
- Q9HBA0
- Pathways
- Hormone Transport, Cell-Cell Junction Organization
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