TRPM2 Antikörper (AA 60-119)

Produktnummer ABIN7172859

Produktdetails anti-TRPM2 Antikörper

Target: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Bindungsspezifität: AA 60-119

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transient receptor potential cation channel subfamily M member 2 protein (60-119AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRPM2

Target: TRPM2 (Transient Receptor Potential Cation Channel, Subfamily M, Member 2 (TRPM2))

Andere Bezeichnung: TRPM2 (TRPM2 Produkte)

Synonyme: EREG1 antikoerper, KNP3 antikoerper, LTRPC2 antikoerper, NUDT9H antikoerper, NUDT9L1 antikoerper, TRPC7 antikoerper, Trpm2-predicted antikoerper, TRPM2 antikoerper, si:ch73-263b18.1 antikoerper, 9830168K16Rik antikoerper, C79133 antikoerper, Trp7 antikoerper, Trrp7 antikoerper, transient receptor potential cation channel subfamily M member 2 antikoerper, transient receptor potential cation channel, subfamily M, member 2 antikoerper, transient receptor potential cation channel subfamily C member 7 antikoerper, TRPM2 antikoerper, Trpm2 antikoerper, trpm2 antikoerper, TRPC7 antikoerper

Hintergrund:

Background: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

Aliases: EREG 1 antibody, EREG1 antibody, Estrogen responsive element associated gene 1 antibody, Estrogen responsive element associated gene 1 protein antibody, Estrogen-responsive element-associated gene 1 protein antibody, KNP 3 antibody, KNP3 antibody, Long transient receptor potential channel 2 antibody, LTRPC 2 antibody, LTrpC-2 antibody, LTrpC2 antibody, MGC133383 antibody, NUDT9H antibody, NUDT9L1 antibody, putative Ca2+ channel protein antibody, putative Ca2+ channel protein antibody, Transient receptor potential cation channel subfamily M member 2 antibody, Transient receptor potential channel 7 antibody, TRPC 7 antibody, TrpC7 antibody, TRPM 2 antibody, Trpm2 antibody, TRPM2_HUMAN antibody

UniProt: O94759