SPOP-B Antikörper (AA 48-374)
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- Target Alle SPOP-B Antikörper anzeigen
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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Bindungsspezifität
- AA 48-374
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPOP-B Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Speckle-type POZ protein (48-374AA)
- Isotyp
- IgG
- Top Product
- Discover our top product SPOP-B Primärantikörper
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anti-Speckle-Type POZ Protein (SPOP-B) (Internal Region) antibody
SPOP-B Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (Center) antibodySPOP-B Reaktivität: Human, Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 301-374) antibodySPOP-B Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3E2 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (C-Term) antibodySPOP-B Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 74-107), (N-Term) antibodySPOP-B Reaktivität: Maus, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal RB49885 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 175-374) antibodySPOP-B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-270) antibodySPOP-B Reaktivität: Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) antibodySPOP-B Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Andere Bezeichnung
- SPOP (SPOP-B Produkte)
- Synonyme
- BTBD32 antikoerper, TEF2 antikoerper, AI315626 antikoerper, Pcif1 antikoerper, zgc:64140 antikoerper, spop antikoerper, tef2 antikoerper, speckle type BTB/POZ protein antikoerper, speckle-type POZ protein antikoerper, speckle type POZ protein S homeolog antikoerper, SPOP antikoerper, Spop antikoerper, spop antikoerper, spop.S antikoerper
- Hintergrund
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Background: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.
Aliases: BTBD32 antibody, HIB homolog 1 antibody, Roadkill homolog 1 antibody, Speckle type POZ protein antibody, Speckle-type POZ protein antibody, SPOP antibody, SPOP_HUMAN antibody, TEF 2 antibody, TEF2 antibody
- UniProt
- O43791
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