DROSHA Antikörper (AA 1-100) (Biotin)

Produktnummer ABIN7168100

Produktdetails anti-DROSHA Antikörper (Biotin)

Target: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DROSHA Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human Ribonuclease 3 protein (1-100AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DROSHA

Target: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Andere Bezeichnung: DROSHA (DROSHA Produkte)

Synonyme: im:7150667 antikoerper, zgc:158612 antikoerper, ETOHI2 antikoerper, HSA242976 antikoerper, RANSE3L antikoerper, RN3 antikoerper, RNASE3L antikoerper, RNASEN antikoerper, 1110013A17Rik antikoerper, AI874853 antikoerper, Etohi2 antikoerper, Rn3 antikoerper, Rnasen antikoerper, RGD1307626 antikoerper, ribonuclease type III, nuclear antikoerper, Ribonuclease 3 antikoerper, ribonuclease 3 antikoerper, drosha ribonuclease III antikoerper, drosha, ribonuclease type III antikoerper, rnasen antikoerper, Thicy_0885 antikoerper, Sinme_0866 antikoerper, Isova_2087 antikoerper, Sphch_0770 antikoerper, DROSHA antikoerper, Drosha antikoerper

Hintergrund:

Background: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3\' and 5\' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.

Aliases: DROSHA antibody, Drosha double stranded RNA specific endoribonuclease antibody, Drosha ribonuclease type III antibody, Etohi2 antibody, HSA242976 antibody, Nuclear RNase III Drosha antibody, p241 antibody, Protein Drosha antibody, Putative protein p241 which interacts with transcription factor Sp1 antibody, Putative ribonuclease III antibody, RANSE3L antibody, Ribonuclease 3 antibody, Ribonuclease III antibody, Ribonuclease III nuclear antibody, Ribonuclease type III nuclear antibody, RibonucleaseIII antibody, RN 3 antibody, RN3 antibody, RNase 3 antibody, RNase III antibody, RNase3 antibody, RNASE3L antibody, RNaseIII antibody, RNASEN antibody, RNC_HUMAN antibody

UniProt: Q9NRR4

Pathways: Regulatorische RNA Pathways