PTPRB Antikörper (AA 1758-1997)
-
- Target Alle PTPRB Antikörper anzeigen
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
-
Bindungsspezifität
- AA 1758-1997
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PTPRB Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Receptor-type tyrosine-protein phosphatase beta protein (1758-1997AA)
- Isotyp
- IgG
- Top Product
- Discover our top product PTPRB Primärantikörper
-
-
- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
- Andere Bezeichnung
- PTPRB (PTPRB Produkte)
- Synonyme
- PTPRB antikoerper, HPTP-BETA antikoerper, HPTPB antikoerper, PTPB antikoerper, R-PTP-BETA antikoerper, VEPTP antikoerper, 3230402H02Rik antikoerper, C130094E24 antikoerper, Ptpz antikoerper, Rptpb antikoerper, VE-PTP antikoerper, Veptp antikoerper, protein tyrosine phosphatase, receptor type B antikoerper, receptor-type tyrosine-protein phosphatase beta antikoerper, protein tyrosine phosphatase, receptor type, B antikoerper, PTPRB antikoerper, LOC100380677 antikoerper, Ptprb antikoerper
- Hintergrund
-
Background: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity).
Aliases: HPTP BETA antibody, HPTPB antibody, Phosphacan receptor type B antibody, Protein tyrosine phosphatase receptor type B antibody, Protein-tyrosine phosphatase beta antibody, PTPB antibody, Ptprb antibody, PTPRB_HUMAN antibody, R PTP BETA antibody, R-PTP-beta antibody, Receptor-type tyrosine-protein phosphatase beta antibody, RPTPB antibody, Vascular endothelial protein tyrosine phosphatase antibody, VE-PTP antibody
- UniProt
- P23467
-