QTRT1 Antikörper (Catalytic Subunit 1)

Produktnummer ABIN7166918

Produktdetails anti-QTRT1 Antikörper

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Bindungsspezifität: AA 211-403, Catalytic Subunit 1

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser QTRT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu QTRT1

Target: QTRT1 (Queuine tRNA-Ribosyltransferase 1 (QTRT1))

Andere Bezeichnung: QTRT1 (QTRT1 Produkte)

Synonyme: CG4947 antikoerper, Dmel\\CG4947 antikoerper, TGT antikoerper, tgt antikoerper, zgc:66378 antikoerper, FP3235 antikoerper, TGUT antikoerper, 2610028E17Rik antikoerper, Tgt antikoerper, Tgut antikoerper, tRNA-guanine transglycosylase antikoerper, queuine tRNA-ribosyltransferase 1 S homeolog antikoerper, queuine tRNA-ribosyltransferase 1 antikoerper, queuine tRNA-ribosyltransferase catalytic subunit 1 antikoerper, Tgt antikoerper, Olsu_0732 antikoerper, Palpr_1298 antikoerper, Riean_1227 antikoerper, Calni_1240 antikoerper, Ftrac_0312 antikoerper, Ocepr_1541 antikoerper, Sulku_0977 antikoerper, Tmar_0854 antikoerper, Bache_2323 antikoerper, Nitsa_1291 antikoerper, Isop_1657 antikoerper, Despr_0021 antikoerper, Pedsa_1842 antikoerper, Corgl_1148 antikoerper, Mahau_0921 antikoerper, Theth_0831 antikoerper, qtrt1.S antikoerper, qtrt1 antikoerper, QTRT1 antikoerper, Qtrt1 antikoerper

Hintergrund:

Background: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1\\\' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1\\\' of the ribose to form the product (By similarity).

Aliases: FP3235 antibody, Guanine insertion enzyme antibody, qtrt1 antibody, Queuine tRNA ribosyltransferase 1 antibody, Queuine tRNA ribosyltransferase antibody, Queuine tRNA-ribosyltransferase antibody, TGT antibody, TGT, 43 KD subunit antibody, TGT, catalytic subunit antibody, TGT_HUMAN antibody, TGUT antibody, tRNA guanine transglycosylase antibody, tRNA-guanine transglycosylase antibody

UniProt: Q9BXR0

Pathways: Ribonucleoside Biosynthetic Process