KCNC3 Antikörper (AA 638-745) (Biotin)

Produktnummer ABIN7163970

Produktdetails anti-KCNC3 Antikörper (Biotin)

Target: KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))

Bindungsspezifität: AA 638-745

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNC3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Potassium voltage-gated channel subfamily C member 3 protein (638-745AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KCNC3

Target: KCNC3 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 3 (KCNC3))

Andere Bezeichnung: KCNC3 (KCNC3 Produkte)

Synonyme: kcnc3-A antikoerper, Kv3.1 antikoerper, KShIIID antikoerper, Kcr2-3 antikoerper, Kv3.3 antikoerper, KSHIIID antikoerper, KV3.3 antikoerper, SCA13 antikoerper, kcnc1 antikoerper, kshiiid antikoerper, kv3.3 antikoerper, sca13 antikoerper, potassium voltage-gated channel subfamily C member 3 antikoerper, potassium channel, voltage gated Shaw related subfamily C, member 1 S homeolog antikoerper, potassium voltage gated channel, Shaw-related subfamily, member 3 antikoerper, potassium channel, voltage gated Shaw related subfamily C, member 3 L homeolog antikoerper, potassium voltage-gated channel, Shaw-related subfamily, member 3 antikoerper, KCNC3 antikoerper, kcnc1.S antikoerper, Kcnc3 antikoerper, kcnc3.L antikoerper

Hintergrund:

Background: Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. The channel displays rapid activation and inactivation kinetics (PubMed:10712820, PubMed:26997484, PubMed:22289912, PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). It plays a role in the regulation of the frequency, shape and duration of action potentials in Purkinje cells. Required for normal survival of cerebellar neurons, probably via its role in regulating the duration and frequency of action potentials that in turn regulate the activity of voltage-gated Ca(2+) channels and cellular Ca(2+) homeostasis (By similarity). Required for normal motor function (PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). Plays a role in the reorganization of the cortical actin cytoskeleton and the formation of actin veil structures in neuronal growth cones via its interaction with HAX1 and the Arp2/3 complex (PubMed:26997484).

Aliases: Kcnc3 antibody, KCNC3_HUMAN antibody, KSHIIID antibody, KV3.3 antibody, Potassium voltage gated channel Shaw related subfamily member 3 antibody, Potassium voltage gated channel subfamily C member 3 antibody, Potassium voltage-gated channel subfamily C member 3 antibody, SCA13 antibody, Shaw related subfamily, member 3 antibody, Shaw related voltage gated potassium channel protein 3 antibody, Spinocerebellar ataxia 13 antibody, Voltage gated potassium channel protein KV3.3 antibody, Voltage gated potassium channel subunit Kv3.3 antibody, Voltage-gated potassium channel subunit Kv3.3 antibody

UniProt: Q14003