ATP8A2 Antikörper (AA 358-570) (HRP)

Produktnummer ABIN7163373

Produktdetails anti-ATP8A2 Antikörper (HRP)

Target: ATP8A2 (ATPase, Class I, Type 8A, Member 2 (ATP8A2))

Bindungsspezifität: AA 358-570

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP8A2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phospholipid-transporting ATPase IB protein (358-570AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ATP8A2

Target: ATP8A2 (ATPase, Class I, Type 8A, Member 2 (ATP8A2))

Andere Bezeichnung: ATP8A2 (ATP8A2 Produkte)

Synonyme: AI415030 antikoerper, Atpc1b antikoerper, Ib antikoerper, ATP antikoerper, ATPIB antikoerper, CAMRQ4 antikoerper, IB antikoerper, ML-1 antikoerper, ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 antikoerper, ATPase phospholipid transporting 8A2 antikoerper, Atp8a2 antikoerper, ATP8A2 antikoerper

Hintergrund:

Background: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Reconstituted to liposomes, the ATP8A2:TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). Proposed to function in the generation and maintenance of phospholipid asymmetry in photoreceptor disk membranes and neuronal axon membranes. May be involved in vesicle trafficking in neuronal cells. Involved in regulation of neurite outgrowth, acting in synergy with TMEM30A. Required for normal visual and auditory function, involved in photoreceptor and inner ear spiral ganglion cell survival.

Aliases: AT8A2_HUMAN antibody, ATP antibody, Atp8a2 antibody, ATPase aminophospholipid transporter class I type 8A member 2 antibody, ATPase aminophospholipid transporter like class I type 8A member 2 antibody, ATPase class I type 8A member 2 antibody, ATPase phospholipid transporting 8A2 antibody, ATPIB antibody, CAMRQ4 antibody, EC=3.6.3.1 antibody, IB antibody, ML-1 antibody, ML1 antibody, P4 ATPase flippase complex alpha subunit ATP8A2 antibody, Probable phospholipid-transporting ATPase IB antibody

UniProt: Q9NTI2