PLA2G2A Antikörper (AA 21-144)

Produktnummer ABIN7163321

Produktdetails anti-PLA2G2A Antikörper

Target: PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))

Bindungsspezifität: AA 21-144

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G2A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PLA2G2A

Target: PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))

Andere Bezeichnung: PLA2G2A (PLA2G2A Produkte)

Synonyme: MOM1 antikoerper, PLA2 antikoerper, PLA2B antikoerper, PLA2L antikoerper, PLA2S antikoerper, PLAS1 antikoerper, sPLA2 antikoerper, EF antikoerper, Mom1 antikoerper, Pla2 antikoerper, sPla2-IIA antikoerper, phospholipase A2 group IIA antikoerper, phospholipase A2, group IIA (platelets, synovial fluid) antikoerper, PLA2G2A antikoerper, Pla2g2a antikoerper

Hintergrund:

Background: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).

Aliases: EC 3.1.1.4 antibody, GIIC sPLA2 antibody, Group IIA phospholipase A2 antibody, membrane associated antibody, Modifier of MIN 1 mouse homolog antibody, MOM1 antibody, Non-pancreatic secretory phospholipase A2 antibody, NPS PLA2 antibody, NPS-PLA2 antibody, PA2GA_HUMAN antibody, Phosphatidylcholine 2-acylhydrolase 2A antibody, Phosphatidylcholine 2acylhydrolase antibody, Phospholipase A2 antibody, Phospholipase A2 group IIA (platelets, synovial fluid) antibody, Phospholipase A2 membrane associated antibody, Phospholipase A2 polypeptide B antibody, Phospholipase A2 synovial antibody, PLA2 antibody, PLA2B antibody, PLA2G2A antibody, PLA2L antibody, PLA2S antibody, PLAS1 antibody, RASF A antibody, sPLA2 antibody

UniProt: P14555

Pathways: Stem Cell Maintenance, Inositol Metabolic Process