PKC theta Antikörper (pSer695) (Cy5.5)
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- Target Alle PKC theta (PRKCQ) Antikörper anzeigen
- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
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Bindungsspezifität
- pSer695
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PKC theta Antikörper ist konjugiert mit Cy5.5
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from mouse PRKCQ around the phosphorylation site of Ser695
- Isotyp
- IgG
- Top Product
- Discover our top product PRKCQ Primärantikörper
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- Applikationshinweise
- IF(IHC-P) 1:50-200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
- Andere Bezeichnung
- Prkcq (PRKCQ Produkte)
- Synonyme
- PRKCT antikoerper, nPKC-theta antikoerper, A130035A12Rik antikoerper, AW494342 antikoerper, PKC-0 antikoerper, PKC-theta antikoerper, PKCtheta antikoerper, Pkcq antikoerper, protein kinase C theta antikoerper, protein kinase C eta antikoerper, protein kinase C, theta antikoerper, PRKCQ antikoerper, PRKCH antikoerper, Prkcq antikoerper
- Hintergrund
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Synonyms: PRKCQphospho S695, PKCSer695, PKC thetaphospho S695, PKC 0, PRKCQ, PKC0, Prkcq, PRKCT, Protein kinase C theta, Protein kinase C theta type, Protein Kinase Ctheta, KPCT_HUMAN, nPKC theta, nPKC-theta, nPKCtheta.
Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
- Gen-ID
- 18761
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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