KHDRBS2 Antikörper (AA 1-349) (HRP)

Produktnummer ABIN7157481

Produktdetails anti-KHDRBS2 Antikörper (HRP)

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Bindungsspezifität: AA 1-349

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KHDRBS2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human KH domain-containing, RNA-binding, signal transduction-associated protein 2 protein (1-349AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu KHDRBS2

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Andere Bezeichnung: KHDRBS2 (KHDRBS2 Produkte)

Synonyme: slm1 antikoerper, slm-1 antikoerper, MGC145973 antikoerper, ba535f17.1 antikoerper, zgc:153588 antikoerper, SLM-1 antikoerper, SLM1 antikoerper, bA535F17.1 antikoerper, 6330586C16Rik antikoerper, Slim1 antikoerper, Slm1 antikoerper, KH RNA binding domain containing, signal transduction associated 2 antikoerper, KH domain containing, RNA binding, signal transduction associated 2 antikoerper, KHDRBS2 antikoerper, khdrbs2 antikoerper, Khdrbs2 antikoerper

Hintergrund:

Background: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.

Aliases: KH domain containing, RNA binding, signal transduction associated protein 2 antibody, 6330586C16Rik antibody, bA535F17.1 antibody, FLJ38664 antibody, hSLM 1 antibody, hSLM-1 antibody, KH domain containing, RNA binding, signal transduction associated 2 antibody, KH domain-containing antibody, KHDR2_HUMAN antibody, khdrbs2 antibody, MGC26664 antibody, RNA-binding antibody, Sam68 like mammalian protein 1 antibody, Sam68-like mammalian protein 1 antibody, signal transduction-associated protein 2 antibody, SLM 1 antibody, SLM-1 antibody, SLM1 antibody

UniProt: Q5VWX1