IL28RA Antikörper (AA 21-228)

Produktnummer ABIN7156606

Produktdetails anti-IL28RA Antikörper

Target: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Bindungsspezifität: AA 21-228

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL28RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Interferon lambda receptor 1 protein (21-228AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IL28RA

Target: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Andere Bezeichnung: IFNLR1 (IL28RA Produkte)

Synonyme: IFNLR1 antikoerper, IL28RA antikoerper, crf2/12 antikoerper, ifnlr antikoerper, il-28r1 antikoerper, il28ra antikoerper, licr2 antikoerper, ifnlr1 antikoerper, CRF2-12 antikoerper, Il28ra antikoerper, CRF2/12 antikoerper, IFNLR antikoerper, IL-28R1 antikoerper, LICR2 antikoerper, RGD1562689 antikoerper, interferon lambda receptor 1 antikoerper, interferon, lambda receptor 1 antikoerper, interferon, lambda receptor 1 L homeolog antikoerper, IFNLR1 antikoerper, ifnlr1 antikoerper, ifnlr1.L antikoerper, Ifnlr1 antikoerper

Hintergrund:

Background: The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.

Aliases: IFNLR1 antibody, IL28RA antibody, LICR2 antibody, Interferon lambda receptor 1 antibody, IFN-lambda receptor 1 antibody, IFN-lambda-R1 antibody, Cytokine receptor class-II member 12 antibody, Cytokine receptor family 2 member 12 antibody, CRF2-12 antibody, Interleukin-28 receptor subunit alpha antibody, IL-28 receptor subunit alpha antibody, IL-28R-alpha antibody, IL-28RA antibody, Likely interleukin or cytokine receptor 2 antibody, LICR2 antibody

UniProt: Q8IU57