IGHA2 Antikörper (AA 36-111)

Produktnummer ABIN7156081

Produktdetails anti-IGHA2 Antikörper

Target: IGHA2 (Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2))

Bindungsspezifität: AA 36-111

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGHA2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IGHA2

Target: IGHA2 (Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2))

Andere Bezeichnung: IGHA2 (IGHA2 Produkte)

Synonyme: immunoglobulin heavy constant alpha 2 (A2m marker) antikoerper, IGHA2 antikoerper

Hintergrund:

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).

Aliases: IGHA2Immunoglobulin heavy constant alpha 2 antibody, Ig alpha-2 chain C region antibody, Ig alpha-2 chain C region BUT antibody, Ig alpha-2 chain C region LAN antibody

UniProt: P01877