RNF5 Antikörper (AA 1-120)

Produktnummer ABIN7151202

Produktdetails anti-RNF5 Antikörper

Target: RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

Bindungsspezifität: AA 1-120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF5 protein (1-120AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RNF5

Target: RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))

Andere Bezeichnung: RNF5 (RNF5 Produkte)

Synonyme: 2410131O05Rik antikoerper, AA407576 antikoerper, NG2 antikoerper, RING5 antikoerper, RMA1 antikoerper, ring finger protein 5 antikoerper, Rnf5 antikoerper, RNF5 antikoerper

Hintergrund:

Background: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the \\\'Lys-63\\\'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the \\\'Lys-48\\\'-linked polyubiquitination of TMEM173 at \\\'Lys-150\\\' leading to its proteasomal degradation, the ubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses.

Aliases: E3 ubiquitin protein ligase RNF5 antibody, E3 ubiquitin-protein ligase RNF5 antibody, G16 antibody, HsRma1 antibody, NG2 antibody, OTTHUMP00000029107 antibody, Protein G16 antibody, Ram1 homolog antibody, RING finger protein 5 antibody, RING5 antibody, RMA1 antibody, RNF 5 antibody, RNF5 antibody, RNF5_HUMAN antibody

UniProt: Q99942