DNAJC3 Antikörper (AA 277-496)

Produktnummer ABIN7150550

Produktdetails anti-DNAJC3 Antikörper

Target: DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))

Bindungsspezifität: AA 277-496

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DnaJ homolog subfamily C member 3 protein (277-496AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DNAJC3

Target: DNAJC3 (DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3))

Andere Bezeichnung: DNAJC3 (DNAJC3 Produkte)

Synonyme: ERdj6 antikoerper, HP58 antikoerper, P58 antikoerper, P58IPK antikoerper, PRKRI antikoerper, zgc:56356 antikoerper, zgc:77731 antikoerper, wu:fb64f06 antikoerper, DNAJC3 antikoerper, dnajc3 antikoerper, DDBDRAFT_0186884 antikoerper, DDBDRAFT_0233602 antikoerper, DDB_0186884 antikoerper, DDB_0233602 antikoerper, cg8286 antikoerper, AA408985 antikoerper, AU067833 antikoerper, Dnajc3a antikoerper, Dnajc3b antikoerper, Prkri antikoerper, mp58 antikoerper, p58 antikoerper, p58IPK antikoerper, fc17a06 antikoerper, prkri antikoerper, wu:fc17a06 antikoerper, DnaJ heat shock protein family (Hsp40) member C3 antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 3a antikoerper, DNAJ heat shock N-terminal domain-containing protein antikoerper, DnaJ heat shock protein family (Hsp40) member C3 L homeolog antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 3b antikoerper, DNAJC3 antikoerper, dnajc3a antikoerper, dnajc3 antikoerper, dnajc3.L antikoerper, Dnajc3 antikoerper, dnajc3b antikoerper

Hintergrund:

Background: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at \\\'Ser-52\\\' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.

Aliases: DnaJ (Hsp40) homolog subfamily C member 3 antibody, DnaJ homolog subfamily C member 3 antibody, DNAJC3 antibody, DNJC3_HUMAN antibody, double-stranded RNA-activated protein kinase inhibitor antibody, Endoplasmic reticulum DnaJ protein 6 antibody, ERdj6 antibody, HP58 antibody, Interferon induced, double stranded RNA activated protein kinase inhibitor antibody, Interferon-induced antibody, P58 antibody, p58 ipk antibody, P58IPK antibody, PRKRI antibody, Protein kinase inhibitor of 58 kDa antibody, Protein kinase inhibitor p58 antibody, Protein kinase interferon inducible double stranded RNA dependent inhibitor antibody

UniProt: Q13217

Pathways: ER-Nucleus Signaling