DNAJC1 Antikörper (AA 521-793)

Produktnummer ABIN7150537

Produktdetails anti-DNAJC1 Antikörper

Target: DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1 (DNAJC1))

Bindungsspezifität: AA 521-793

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNAJC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Ratte

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human DnaJ homolog subfamily C member 10 protein (521-793AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DNAJC1

Target: DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1 (DNAJC1))

Andere Bezeichnung: DNAJC1 (DNAJC1 Produkte)

Synonyme: dnajc1l antikoerper, zgc:152779 antikoerper, DNAJL1 antikoerper, ERdj1 antikoerper, HTJ1 antikoerper, MTJ1 antikoerper, 4733401K02Rik antikoerper, AA960110 antikoerper, D230036H06Rik antikoerper, Dnajl1 antikoerper, ERj1p antikoerper, DnaJ heat shock protein family (Hsp40) member C1 antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 1 antikoerper, DnaJ heat shock protein family (Hsp40) member C1 S homeolog antikoerper, dnajc1 antikoerper, DNAJC1 antikoerper, Dnajc1 antikoerper, dnajc1.S antikoerper

Hintergrund:

Background: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.

Aliases: DNAJC10 antibody, ERDJ5 antibody, UNQ495/PRO1012DnaJ homolog subfamily C member 10 antibody, EC 1.8.4.- antibody, Endoplasmic reticulum DNA J domain-containing protein 5 antibody, ER-resident protein ERdj5 antibody, ERdj5 antibody, Macrothioredoxin antibody, MTHr antibody

UniProt: Q8IXB1

Pathways: Chromatin Binding