POLR3F Antikörper (AA 1-270) (HRP)

Produktnummer ABIN7150469

Produktdetails anti-POLR3F Antikörper (HRP)

Target: POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))

Bindungsspezifität: AA 1-270

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR3F Antikörper ist konjugiert mit HRP

Applikation: ELISA

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLR3F

Target: POLR3F (Polymerase (RNA) III (DNA Directed) Polypeptide F, 39 KDa (POLR3F))

Andere Bezeichnung: POLR3F (POLR3F Produkte)

Synonyme: 2810411G20Rik antikoerper, 3010019O03Rik antikoerper, 3110032A07Rik antikoerper, RPC39 antikoerper, RPC6 antikoerper, zgc:56299 antikoerper, zgc:76983 antikoerper, RNA polymerase III subunit F antikoerper, polymerase (RNA) III (DNA directed) polypeptide F antikoerper, POLR3F antikoerper, Polr3f antikoerper, polr3f antikoerper

Hintergrund:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Aliases: DNA directed RNA polymerase III 39 kDa polypeptide antibody, DNA directed RNA polymerase III 39 kDa polypeptide F antibody, DNA directed RNA polymerase III subunit F antibody, DNA directed RNA polymerase III subunit RPC6 antibody, DNA directed RNA polymerases III 39 kDa polypeptide antibody, DNA-directed RNA polymerase III subunit F antibody, DNA-directed RNA polymerase III subunit RPC6 antibody, MGC13517 antibody, Polr3f antibody, Polymerase (RNA) III (DNA directed) polypeptide F antibody, RNA polymerase III 39 kDa subunit antibody, RNA polymerase III C39 subunit antibody, RNA polymerase III subunit C6 antibody, RPC 39 antibody, RPC 6 antibody, RPC39 antibody, RPC6 antibody, RPC6_HUMAN antibody

UniProt: Q9H1D9