APOBEC3D Antikörper (AA 250-371)
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- Target Alle APOBEC3D Antikörper anzeigen
- APOBEC3D (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
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Bindungsspezifität
- AA 250-371
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser APOBEC3D Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human DNA dC->dU-editing enzyme APOBEC-3D protein (250-371AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- APOBEC3D (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3D (APOBEC3D))
- Andere Bezeichnung
- APOBEC3D (APOBEC3D Produkte)
- Synonyme
- A3D antikoerper, APOBEC3DE antikoerper, APOBEC3E antikoerper, ARP6 antikoerper, APOBEC3D antikoerper, apolipoprotein B mRNA editing enzyme catalytic subunit 3D antikoerper, APOBEC3D antikoerper
- Hintergrund
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Background: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons.
Aliases: A3D antibody, ABC3D_HUMAN antibody, APOBEC3D antibody, APOBEC3DE antibody, APOBEC3E antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene antibody, ARP6 antibody, bK150C2.9 antibody, BK150C2.9 protein antibody, DNA dC >dU editing enzyme APOBEC 3D antibody, DNA dC->dU-editing enzyme APOBEC-3D antibody, hCG_41704 antibody, HCG41704, isoform CRA_b antibody, Probable DNA dC->dU-editing enzyme APOBEC-3D antibody
- UniProt
- Q96AK3
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