Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2) (AA 82-329) Antikörper (FITC)

Produktnummer ABIN7149381

Produktdetails

Target: Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)

Bindungsspezifität: AA 82-329

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)

Andere Bezeichnung: CASTOR2

Hintergrund:

Background: Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

Aliases: CASTOR2 antibody, Cellular arginine sensor for mTORC1 protein 2 antibody, GATL2_HUMAN antibody, GATS-like protein 2 antibody, GATSL2 antibody

UniProt: A6NHX0