CYP3A4 Antikörper (AA 259-441)

Produktnummer ABIN7149259

Produktdetails anti-CYP3A4 Antikörper

Target: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Bindungsspezifität: AA 259-441

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP3A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cytochrome P450 3A4 protein (259-441AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CYP3A4

Target: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Andere Bezeichnung: CYP3A4 (CYP3A4 Produkte)

Synonyme: CP33 antikoerper, CP34 antikoerper, CYP3A antikoerper, CYP3A3 antikoerper, CYPIIIA3 antikoerper, CYPIIIA4 antikoerper, HLP antikoerper, NF-25 antikoerper, P450C3 antikoerper, P450PCN1 antikoerper, MGC108372 antikoerper, CYP3A80 antikoerper, CYP3A4 antikoerper, CYP3A21 antikoerper, CYPIIIA21 antikoerper, CYP3A12 antikoerper, cytochrome P450 family 3 subfamily A member 4 antikoerper, cytochrome P450 family 3 subfamily A member 43 antikoerper, cytochrome P450 3A4 antikoerper, cytochrome P450, subfamily IIIA, polypeptide 4 antikoerper, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antikoerper, cytochrome P450, family 3, subfamily A, polypeptide 4 antikoerper, CYP3A4 antikoerper, CYP3A43 antikoerper, PTRG_01782 antikoerper, PTRG_06060 antikoerper, cyp3a4 antikoerper

Hintergrund:

Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1\\\'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).

Aliases: 1,8-cineole 2-exo-monooxygenase antibody, Albendazole monooxygenase antibody, Albendazole sulfoxidase antibody, CP33 antibody, CP34 antibody, CP3A4_HUMAN antibody, CYP3 antibody, CYP3A antibody, CYP3A3 antibody, CYP3A4 antibody, CYPIIIA3 antibody, CYPIIIA4 antibody, Cytochrome P450 3A3 antibody, Cytochrome P450 3A4 antibody, Cytochrome P450 family 3 subfamily A polypeptide 4 antibody, Cytochrome P450 HLp antibody, Cytochrome P450 NF-25 antibody, Cytochrome P450 subfamily IIIA polypeptide 4 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody, Cytochrome P450-PCN1 antibody, Glucocorticoid inducible P450 antibody, HLP antibody, MGC126680 antibody, NF 25 antibody, NF25 antibody, Nifedipine oxidase antibody, P450 III steroid inducible antibody, P450 PCN1 antibody, P450, family III antibody, P450C3 antibody, P450PCN1 antibody, Quinine 3 monooxygenase antibody, Quinine 3-monooxygenase antibody, Taurochenodeoxycholate 6 alpha hydroxylase antibody, Taurochenodeoxycholate 6-alpha-hydroxylase antibody

UniProt: P08684

Pathways: Steroid Hormone Biosynthesis