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COL4a2 Antikörper (AA 1493-1712)

COL4A2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7148243
  • Target Alle COL4a2 (COL4A2) Antikörper anzeigen
    COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
    Bindungsspezifität
    • 15
    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1493-1712
    Reaktivität
    • 46
    • 9
    • 3
    Human
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COL4a2 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 23
    • 14
    • 13
    • 13
    • 10
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Collagen alpha-2(IV) chain protein (1493-1712AA)
    Isotyp
    IgG
    Top Product
    Discover our top product COL4A2 Primärantikörper
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
    Andere Bezeichnung
    COL4A2 (COL4A2 Produkte)
    Synonyme
    col4a2-a antikoerper, zCanstatin antikoerper, ICH antikoerper, POREN2 antikoerper, Col4a-2 antikoerper, collagen, type IV, alpha 2 L homeolog antikoerper, collagen type IV alpha 2 chain antikoerper, collagen, type IV, alpha 2 antikoerper, col4a2.L antikoerper, COL4A2 antikoerper, col4a2 antikoerper, Col4a2 antikoerper
    Hintergrund

    Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a \\\'chicken-wire\\\' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

    Aliases: Canstatin antibody, CO4A2_HUMAN antibody, COL4A 2 antibody, Col4a2 antibody, Collagen alpha 2(IV) chain antibody, Collagen, type IV, alpha 2 antibody

    UniProt
    P08572
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