COL4a2 Antikörper (AA 1493-1712)
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- Target Alle COL4a2 (COL4A2) Antikörper anzeigen
- COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
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Bindungsspezifität
- AA 1493-1712
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser COL4a2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Collagen alpha-2(IV) chain protein (1493-1712AA)
- Isotyp
- IgG
- Top Product
- Discover our top product COL4A2 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
- Andere Bezeichnung
- COL4A2 (COL4A2 Produkte)
- Synonyme
- col4a2-a antikoerper, zCanstatin antikoerper, ICH antikoerper, POREN2 antikoerper, Col4a-2 antikoerper, collagen, type IV, alpha 2 L homeolog antikoerper, collagen type IV alpha 2 chain antikoerper, collagen, type IV, alpha 2 antikoerper, col4a2.L antikoerper, COL4A2 antikoerper, col4a2 antikoerper, Col4a2 antikoerper
- Hintergrund
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Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a \\\'chicken-wire\\\' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
Aliases: Canstatin antibody, CO4A2_HUMAN antibody, COL4A 2 antibody, Col4a2 antibody, Collagen alpha 2(IV) chain antibody, Collagen, type IV, alpha 2 antibody
- UniProt
- P08572
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