MRC2 Antikörper (AA 120-300)

Produktnummer ABIN7146098

Produktdetails anti-MRC2 Antikörper

Target: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Bindungsspezifität: AA 120-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRC2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human C-type mannose receptor 2 protein (120-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MRC2

Target: MRC2 (Mannose Receptor, C Type 2 (MRC2))

Andere Bezeichnung: MRC2 (MRC2 Produkte)

Synonyme: MRC2 antikoerper, cd280 antikoerper, uparap antikoerper, clec13e antikoerper, endo180 antikoerper, Endo180 antikoerper, CD280 antikoerper, CLEC13E antikoerper, ENDO180 antikoerper, UPARAP antikoerper, mKIAA0709 antikoerper, uPARAP antikoerper, mannose receptor C type 2 antikoerper, mannose receptor, C type 2 antikoerper, MRC2 antikoerper, mrc2 antikoerper, Mrc2 antikoerper

Hintergrund:

Background: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Aliases: C-type lectin domain family 13 member E antibody, C-type mannose receptor 2 antibody, CD 280 antibody, CD280 antibody, CD280 antigen antibody, CLEC 13E antibody, CLEC13E antibody, ENDO 180 antibody, ENDO180 antibody, Endocytic receptor (macrophage mannose receptor family) antibody, Endocytic receptor 180 antibody, FLJ35911 antibody, KIAA0709 antibody, Macrophage mannose receptor 2 antibody, Mannose receptor C type 2 antibody, MRC 2 antibody, MRC2 antibody, MRC2_HUMAN antibody, UPAR-associated protein antibody, UPARAP antibody, Urokinase plasminogen activator receptor associated protein antibody, Urokinase receptor associated protein antibody, Urokinase receptor-associated protein antibody, Urokinase-type plasminogen activator receptor-associated protein antibody

UniProt: Q9UBG0