CLEC4E Antikörper (AA 41-219) (FITC)

Produktnummer ABIN7146079

Produktdetails anti-CLEC4E Antikörper (FITC)

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Bindungsspezifität: AA 41-219

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLEC4E Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human C-type lectin domain family 4 member E protein (41-219AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CLEC4E

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Andere Bezeichnung: CLEC4E (CLEC4E Produkte)

Synonyme: CLECSF9 antikoerper, MINCLE antikoerper, C86253 antikoerper, Clecsf9 antikoerper, Mincle antikoerper, CLEC4E antikoerper, C-type lectin domain family 4 member E antikoerper, C-type lectin domain family 4, member e antikoerper, C-type lectin domain family 4, member E antikoerper, CLEC4E antikoerper, Clec4e antikoerper, LOC611538 antikoerper

Hintergrund:

Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6\\\'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Aliases: C type lectin domain family 4 member E antibody, C type lectin superfamily member 9 antibody, C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody, C-type lectin domain family 4 member E antibody, C-type lectin superfamily member 9 antibody, CLC4E_HUMAN antibody, CLEC 4E antibody, Clec4e antibody, CLECSF9 antibody, Macrophage inducible C type lectin antibody, Macrophage-inducible C-type lectin antibody, MINCLE antibody

UniProt: Q9ULY5