TNFAIP1 Antikörper (AA 233-316)

Produktnummer ABIN7145827

Produktdetails anti-TNFAIP1 Antikörper

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Bindungsspezifität: AA 233-316

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFAIP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 protein (233-316AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TNFAIP1

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Andere Bezeichnung: TNFAIP1 (TNFAIP1 Produkte)

Synonyme: zgc:55302 antikoerper, wu:fi06b02 antikoerper, TNFAIP1 antikoerper, B12 antikoerper, B61 antikoerper, BTBD34 antikoerper, EDP1 antikoerper, hBACURD2 antikoerper, Edp-1 antikoerper, Edp1 antikoerper, Tnfip1 antikoerper, tumor necrosis factor, alpha-induced protein 1 (endothelial) antikoerper, TNF alpha induced protein 1 antikoerper, TNF alpha induced protein 1 L homeolog antikoerper, tnfaip1 antikoerper, TNFAIP1 antikoerper, Tnfaip1 antikoerper, tnfaip1.L antikoerper

Hintergrund:

Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Aliases: TNFAIP1 antibody, BACURD2 antibody, EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody, hBACURD2 antibody, BTB/POZ domain-containing protein TNFAIP1 antibody, Protein B12 antibody, Tumor necrosis factor antibody, alpha-induced protein 1 antibody, endothelial antibody

UniProt: Q13829