BATF2 Antikörper (AA 1-189)

Produktnummer ABIN7145267

Produktdetails anti-BATF2 Antikörper

Target: BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))

Bindungsspezifität: AA 1-189

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BATF2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Basic leucine zipper transcriptional factor ATF-like 2 protein (1-189AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BATF2

Target: BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))

Andere Bezeichnung: BATF2 (BATF2 Produkte)

Synonyme: RGD1311481 antikoerper, BATF2 antikoerper, SARI antikoerper, 4933430F08Rik antikoerper, basic leucine zipper ATF-like transcription factor 2 antikoerper, basic leucine zipper transcription factor, ATF-like 2 antikoerper, Batf2 antikoerper, BATF2 antikoerper

Hintergrund:

Background: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5\'-TGA[CG]TCA-3\' and regulates expression of target genes. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.

Aliases: BATF2Basic leucine zipper transcriptional factor ATF-like 2 antibody, B-ATF-2 antibody, Suppressor of AP-1 regulated by IFN antibody, SARI antibody

UniProt: Q8N1L9