PtxA (AA 35-269) Antikörper
-
- Target
- PtxA
- Bindungsspezifität
- AA 35-269
- Reaktivität
- Bordetella pertussis
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Unkonjugiert
- Applikation
- ELISA, Western Blotting (WB)
- Kreuzreaktivität
- Bordetella pertussis
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA)
- Isotyp
- IgG
-
anti-PtxA (AA 35-269) antibody
Reaktivität: Bordetella pertussis ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- PtxA
- Hintergrund
-
Background: S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
Aliases: ptxA antibody, BP3783 antibody, Pertussis toxin subunit 1 antibody, PTX S1 antibody, Islet-activating protein S1 antibody, IAP S1 antibody, NAD-dependent ADP-ribosyltransferase antibody, EC 2.4.2.- antibody
- UniProt
- P04977
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