ZAP7 (pTyr319) Antikörper
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- Target
- ZAP7
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Bindungsspezifität
- pTyr319
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
- Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of tyrosine 319 (S-P-Y(p)-S-D) derived from Human Zap-70.
- Isotyp
- IgG
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- Applikationshinweise
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ZAP7
- Hintergrund
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Background:
Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not.
Salomon AR, et al. (2003) Proc Natl Acad Sci U S A, 100(2): 443-448
Ku GM, et al. (2001) EMBO J, 20(3): 457-465
Tang J, et al. (1999) Proc Natl Acad Sci U S A, 96(17): 9775-9780
Zhao Q, et al. (1996) Mol Cell Biol, 16(12): 6765-6774
Williams BL, et al. (1999) EMBO J, 18(7): 1832-1844
Adjali O, et al. (2005) J Clin Invest, 115(8): 2287-2295.Aliases: 70 kDa zeta associated protein antibody, 70 kDa zeta-associated protein antibody, EC 2.7.10.2 antibody, FLJ17670 antibody, FLJ17679 antibody, Selective T cell defect antibody, SRK antibody, STD antibody, Syk related tyrosine kinase antibody, Syk-related tyrosine kinase antibody, Truncated ZAP kinase antibody, Tyrosine protein kinase ZAP70 antibody, Tyrosine-protein kinase ZAP-70 antibody, TZK antibody, ZAP 70 antibody, ZAP70 antibody, ZAP70_HUMAN antibody, Zeta chain associated protein kinase 70kD antibody, Zeta chain associated protein kinase 70 kDa antibody, Zeta chain associated protein kinase 70 kDa isoform 1 antibody, Zeta chain associated protein kinase 70 kDa isoform 2 antibody, Zeta chain of T cell receptor associated protein kinase 70 antibody, Zeta chain TCR associated protein kinase 70kD antibody, Zeta chain TCR associated protein kinase 70 kDa antibody
- UniProt
- P43403
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