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MAP3K7 Antikörper (pThr184)

MAP3K7 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7138788
  • Target Alle MAP3K7 Antikörper anzeigen
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    Bindungsspezifität
    • 18
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr184
    Reaktivität
    • 108
    • 40
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 102
    • 6
    • 1
    Kaninchen
    Klonalität
    • 99
    • 10
    Polyklonal
    Konjugat
    • 68
    • 8
    • 8
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP3K7 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 64
    • 46
    • 16
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    Immunogen
    Peptide sequence around phosphorylation site of threonine 184 (I-Q-T(p)-H-M) derived from Human TAK1.
    Isotyp
    IgG
    Top Product
    Discover our top product MAP3K7 Primärantikörper
  • Applikationshinweise
    WB:1:500-1:3000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
    Andere Bezeichnung
    MAP3K7 (MAP3K7 Produkte)
    Synonyme
    si:ch211-225h9.1 antikoerper, zgc:110612 antikoerper, Tak1 antikoerper, MEKK7 antikoerper, TAK1 antikoerper, TGF1a antikoerper, B430101B05 antikoerper, C87327 antikoerper, mitogen-activated protein kinase kinase kinase 7 antikoerper, mitogen activated protein kinase kinase kinase 7 antikoerper, map3k7 antikoerper, Map3k7 antikoerper, MAP3K7 antikoerper
    Hintergrund

    Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7.

    Aliases: M3K7_HUMAN antibody, MAP3K 7 antibody, Map3k7 antibody, MEKK7 antibody, Mitogen activated protein kinase kinase kinase 7 antibody, Mitogen-activated protein kinase kinase kinase 7 antibody, TAK1 antibody, TGF beta activated kinase 1 antibody, TGF-beta-activated kinase 1 antibody, TGF1a antibody, Transforming growth factor beta activated kinase 1 antibody, Transforming growth factor-beta-activated kinase 1 antibody

    UniProt
    O43318
    Pathways
    NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
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