GRIN2B Antikörper (AA 1250-1254)
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- Target Alle GRIN2B Antikörper anzeigen
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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Bindungsspezifität
- AA 1250-1254
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRIN2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogen
- Peptide sequence around aa.1250-1254(N-L-Y-D-I) derived from Human NMDANR2B Subunit.
- Isotyp
- IgG
- Top Product
- Discover our top product GRIN2B Primärantikörper
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- Applikationshinweise
- WB:1:500-1:1000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
- Andere Bezeichnung
- Grin2b (GRIN2B Produkte)
- Synonyme
- NMDAR2B antikoerper, GluN2B antikoerper, MRD6 antikoerper, NR2B antikoerper, hNR3 antikoerper, nmdar2b antikoerper, nr2b antikoerper, AW490526 antikoerper, Nmdar2b antikoerper, glutamate ionotropic receptor NMDA type subunit 2B antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2B L homeolog antikoerper, glutamate receptor, ionotropic, NMDA2B (epsilon 2) antikoerper, GRIN2B antikoerper, Grin2b antikoerper, grin2b.L antikoerper
- Hintergrund
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Background: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death
Kornau H.C., Schenker L.T., Kennedy M.B., Seeburg P.H.Science 269:1737-1740(1995)
Kurschner C., Mermelstein P.G., Holden W.T., Surmeier D.J.Mol. Cell. Neurosci. 11:161-172(1998)Aliases: Grin2bGlutamate receptor ionotropic antibody, NMDA 2B antibody, GluN2B antibody, Glutamate [NMDA] receptor subunit epsilon-2 antibody, N-methyl D-aspartate receptor subtype 2B antibody, NMDAR2B antibody, NR2B antibody
- UniProt
- Q00960
- Pathways
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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