SRGAP3 Antikörper

Produktnummer ABIN7131182

Produktdetails anti-SRGAP3 Antikörper

Target: SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRGAP3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human SRGAP3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SRGAP3

Target: SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))

Andere Bezeichnung: SRGAP3 (SRGAP3 Produkte)

Synonyme: AI452337 antikoerper, Arhgap14 antikoerper, D130026O08Rik antikoerper, Gbi antikoerper, MEGAP antikoerper, WRP antikoerper, mKIAA0411 antikoerper, RGD1563152 antikoerper, ARHGAP14 antikoerper, SRGAP2 antikoerper, RGD1566016 antikoerper, srGAP2 antikoerper, fnbp2 antikoerper, srgap2 antikoerper, SLIT-ROBO Rho GTPase activating protein 3 antikoerper, SLIT-ROBO Rho GTPase activating protein 2 antikoerper, SLIT-ROBO Rho GTPase activating protein 2 L homeolog antikoerper, Srgap3 antikoerper, SRGAP3 antikoerper, Srgap2 antikoerper, srgap3 antikoerper, srgap2.L antikoerper

Hintergrund:

Background: SRGAP3 is a 1099 amino acid protein containing 1 FCH domain, 1 Rho-GAP domain and 1 SH3 domain. Expressed highly in brain, and in lower levels in kidney, WRP is thought to play a role in cell migration through its interaction with Cdc42 and Rac1. Cdc42 and Rac1 are two intracellular signaling proteins that regulate the multistep cell migration process. WRP downregulates Cdc42 and Rac1 activity, thereby impairing actin and microtubule dynamics, the formation of protrusions, and total cell migration. Defects in the gene encoding WRP have been linked to severe idiopathic mental retardation. Three isoforms of WRP exist as a result of alternative splicing events.

Aliases: ARHGAP 14 antibody, ARHGAP14 antibody, Gbi antibody, ME GAP antibody, MEGAP antibody, Mental disorder associated GAP antibody, Mental disorder-associated GAP antibody, Rho GTPase activating protein 14 antibody, Rho GTPase-activating protein 14 antibody, SLIT ROBO Rho GTPase activating protein 3 antibody, SLIT-ROBO Rho GTPase-activating protein 3 antibody, srGAP 2 antibody, srGAP 3 antibody, srGAP2 antibody, srGAP3 antibody, SRGP 2 antibody, SRGP2 antibody, SRGP3_HUMAN antibody, WAVE associated Rac GTPase activating protein antibody, WAVE-associated Rac GTPase-activating protein antibody, WRP antibody

UniProt: O43295