ZBED1 Antikörper

Produktnummer ABIN7127132

Produktdetails anti-ZBED1 Antikörper

Target: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ZBED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: ZBED1 (zinc finger BED domain-containing protein 1), also known as ALTE (Ac-like transposable element), DREF or TRAMP, is a 694 amino acid protein that localizes specifically to granular structures within the nucleus. Expressed ubiquitously at low levels and present at higher levels in heart, placenta, spleen and skeletal muscle, ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoding genes, thereby playing a role in the cell cycle and in cell proliferation events. ZBED1 contains one BED-type zinc finger and binds specifically to 5'- TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. Additionally, ZBED1 binds strongly to the promotor region of Histone H1 (a protein required for the condensation of nucleosomes into higher order structures), subsequently activating H1 transcription.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human ZBED1 protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ZBED1

Target: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Andere Bezeichnung: ZBED1 (ZBED1 Produkte)

Synonyme: ZBED1 antikoerper, ZBED1P antikoerper, ALTE antikoerper, DREF antikoerper, TRAMP antikoerper, hDREF antikoerper, zinc finger BED-type containing 1 antikoerper, zinc finger, BED-type containing 1 antikoerper, ZBED1 antikoerper, zbed1 antikoerper

Hintergrund: Ac like transposable element, ALTE, BED type zinc finger domain containing protein 1, DNA replication related element binding factor, dREF homolog, hDREF, KIAA0785, Putative Ac-like transposable element, TRAMP, ZBED1, Zinc finger BED domain-containing protein 1,ZBED1 / DREF
Cellular localisation: Nucleus. In granular structures.

Molekulargewicht: 86kDa

Gen-ID: 9189, 131452

UniProt: O96006